Bioinorganic Chemistry
Prof. Aidan McDonald
Introduction to the natural roles metals play in biology |
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| Lecture 1 | Introduction to Bioinorganic Chemistry |
| Lecture 2 | Spectroscopic Techniques in Bioinorganic Chemistry |
| Lecture 3 | Photosynthesis - Photosystem II - manganese, iron, magnesium in biological water oxidation |
| Lecture 4 | Dioxygen Transport - iron and copper, hemoglobin, myoglobin, hemerythrin, hemocyanin |
| Lecture 5 | Dioxygen Activation – heme- and nonheme iron oxidase, and mono- and dicopper oxidases |
| Lecture 6 | Electron Transfer - iron/sulfur clusters, ferrodoxins, cytochrome, aconitase, blue copper |
| Lecture 7 | Hydrogenases - diiron, nickel/iron, mononuclear iron |
| Lecture 8 | Nitrogen Fixation and Bioinorganic Organometallics – Nitrogenase, Cobalamin (Vitamin B12) |
| Lecture 9 | Metals and Reactive Oxygen Species – Catalase, Superoxide reductase and Dismutases, Metals in Alzheimer’s Disease |
| Lecture 10 | Synthetic models in Bioinorganic Chemistry – synthesis and characterization provide insights in enzyme function |
| Tutorials | Tutorials will be held after lectures 5 and 10 |